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Home » Blood Pressure » Guides

Diuretic Drugs For Blood Pressure: Potential Risks and Side Effects

Michael Rotman, MD, FRCPC, PhD

Michael Rotman, MD, FRCPC, PhD | Fact checked by Robin Backlund, BHSc
Last update: February 24, 2023

Not sure if diuretics are safe for managing blood pressure? Learn all about diuretics, their potential side effects, and more in this comprehensive guide.

diuretics for blood pressure

Quick Summary

  • Diuretics may be prescribed to those with edema, high blood pressure, heart failure, kidney difficulties, or liver disorders.
  • By increasing urine production, diuretics help to reduce the amount of fluid in the body, which can help to lower blood pressure and reduce swelling.
  • However, experts say the research on diuretics is conflicting, so people shouldn’t switch drugs until more studies are done.

High blood pressure, commonly known as hypertension, affects millions of people worldwide and is a significant risk factor for serious health problems. For individuals with hypertension, medications such as diuretics can be a crucial component of their treatment plan.

Few pieces of research have shown that diuretics can help lower blood pressure and decrease the risk of complications such as heart attacks and strokes. However, like any medication, diuretics can have side effects, and choosing the right type of diuretic is important for managing hypertension effectively.

This article will explore the role of diuretics in managing high blood pressure, potential side effects, and how to use them safely.

Table of contents hide
1. What Are Diuretics?
1.1. Type of diuretics
2. Who Should Consume Diuretics?
3. How Do Diuretics Affect Blood Pressure?
4. What Are Some Possible Risks And Side Effects Of Consuming Diuretics?
5. How Should You Take Diuretics For Blood Pressure?
6. Conclusion

What Are Diuretics?

Diuretics, or water pills, are medications or substances that increase urine output and decrease the amount of fluid in the body. They are often used to treat hypertension, heart disease, and edema.

Diuretics work by altering the function of the kidneys, which are responsible for filtering the blood and removing excess water and waste products from the body.

Type of diuretics

There are several types of diuretics, including:

  1. Thiazide diuretics: These drugs work on the distal tubules of the kidneys, inhibiting the reabsorption of sodium, which increases urine production. Examples of thiazide diuretics include hydrochlorothiazide and chlorthalidone.
  2. Loop diuretics: Loop diuretics act on the ascending limb of the loop of Henle in the kidneys, where they block the reabsorption of sodium and chloride ions. This results in increased urine output. Examples of loop diuretics include furosemide and bumetanide.
  3. Potassium-sparing diuretics: These diuretics reduce the excretion of potassium and work by blocking the effects of aldosterone, a hormone that regulates sodium and potassium levels in the body. Examples of potassium-sparing diuretics include spironolactone and eplerenone.
  4. Osmotic diuretics: Osmotic diuretics are substances that are not absorbed by the kidneys and remain in the bloodstream, where they increase the osmotic pressure of the blood. This results in water movement from the tissues into the bloodstream, which then gets filtered by the kidneys and excreted as urine. Examples of osmotic diuretics include mannitol and urea.

Each type of diuretic has a slightly different mechanism of action and potential side effects, and the choice of diuretic depends on the condition being treated and the patient’s needs.

Who Should Consume Diuretics?

A doctor may recommend diuretics for individuals with edema, high blood pressure, heart failure, kidney problems, liver problems, or glaucoma. In each of these cases, diuretics can help alleviate symptoms or reduce the risk of complications.

However, it is essential to note that a healthcare provider should always make the decision to use diuretics and can determine whether the benefits outweigh the potential risks and side effects.

Additionally, diuretics should not be used by individuals with certain medical conditions, and they may interact with other medications, so it is crucial to speak with a healthcare provider before taking a diuretic.

How Do Diuretics Affect Blood Pressure?

Diuretics work by inhibiting the reabsorption of sodium in the kidneys, which results in an increase in urine production. Sodium is an important electrolyte that regulates fluid balance in the body, so by reducing the amount of sodium that is reabsorbed, diuretics help in the reduction of fluid amount in the body.

This can help lower blood pressure by reducing the amount of work the heart has to do to pump blood. Moreover, Thiazide and Loop diuretics are the two most commonly used types of diuretics for hypertension.

What Are Some Possible Risks And Side Effects Of Consuming Diuretics?

These are the most common risks and side effects associated with consuming diuretics:

  • Dehydration: Diuretics increase urine output, which can lead to dehydration if the lost fluids are not replaced.
  • Electrolyte imbalances: Diuretics can cause imbalances in electrolytes such as sodium, potassium, and magnesium, which can lead to a range of health problems.
  • Low blood pressure: Diuretics can lower blood pressure, which can cause dizziness or fainting.
  • Gout: Diuretics can increase uric acid in the blood, which can trigger gout attacks in people prone to this condition.
  • Muscle cramps: Diuretics can cause muscle cramps or weakness, especially in people who are deficient in potassium.
  • Sexual dysfunction: Some diuretics can cause sexual dysfunction in men, such as difficulty getting or maintaining an erection.
  • Increased blood sugar: Diuretics can increase blood sugar levels, which can be problematic for people with diabetes.
  • Kidney damage: In rare cases, high doses of diuretics can cause kidney damage or failure.

How Should You Take Diuretics For Blood Pressure?

First, it is important to follow your healthcare provider’s instructions carefully. They will likely prescribe a specific type and dosage of diuretic based on your individual health needs, so it is vital to take the medication exactly as directed.

Diuretics are usually taken once a day in the morning, but the timing and frequency may vary depending on the prescribed medication. Your healthcare provider may also recommend monitoring your blood pressure regularly and may adjust your medication dose if needed to achieve the desired effect.

It is also essential to stay hydrated when taking diuretics, as these medications can increase urine output and lead to dehydration if fluids are not replaced. Drinking plenty of water and other fluid drinks throughout the day can help prevent dehydration and electrolyte imbalances.

Conclusion

Diuretics are a class of medication that can effectively manage high blood pressure by reducing fluid volume in the body. While diuretics can be an effective treatment option for many people, working closely with a healthcare provider is vital to ensure the medication is used safely and effectively.

Additionally, taking diuretics as directed, staying hydrated, and monitoring blood pressure regularly can help ensure the best possible outcomes for people using diuretics to manage their high blood pressure. With proper use and monitoring, diuretics can be crucial in managing hypertension and reducing the risk of related health complications.

References

Cleveland Clinic, “Diuretics” on January 10, 2021 https://my.clevelandclinic.org/health/treatments/21826-diuretics

Nazario, Brunilda “Diuretics (Water Pills) for High Blood Pressure” on September 17, 2021
https://www.webmd.com/hypertension-high-blood-pressure/guide/diuretic-treatment-high-blood-pressure

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Michael Rotman, MD, FRCPC, PhD

About Michael Rotman, MD, FRCPC, PhD

Michael Rotman is a Structural Heart Specialist, Interventional Cardiologist and Scientist. He has more than a decade of experience in treating heart related desease, as well as authoring and reviewing health and wellness-related content. Currently work for a St. Michael’s Hospital in Toronto.

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Fact checked by Robin Backlund, BHSc

robin backlundRobin Backlund is a dedicated journalist and a medical student who has written several articles and essays exposing the falseness and hollowness of online resources in the medical science niche.

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