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Home » Blood Pressure » Guides

High Blood Pressure Can Lead to Kidney Damage

Michael Rotman, MD, FRCPC, PhD

Michael Rotman, MD, FRCPC, PhD | Fact checked by Robin Backlund, BHSc
Last update: December 7, 2022

Kidney damage is a common cause and result of high blood pressure. Discover how the diseases are linked and how to treat them simultaneously.

high blood pressure kidney damage

Quick Summary

  • There is a well-documented connection between high blood pressure and kidney damage.
  • Blood vessels play a pivotal role. However, symptoms of both conditions can often go unnoticed.
  • With medication and adapting your lifestyle, you can prevent kidney disease caused by hypertension.

Most people don’t consider that high blood pressure can lead to kidney damage until they have hypertension or chronic renal disease. Nonetheless, the link has been extensively studied.

The answer can be found in blood vessels. High blood pressure can harden or narrow arteries and veins around the kidneys, compromising blood supply.

Studies suggest that in the USA, every second adult has a blood pressure disorder. Similarly, more than 1 in 7 individuals develop kidney conditions, demonstrating an overlap between the ailments.

This article examines the causes, symptoms, diagnosis, and management of kidney disease concerning high blood pressure.

Table of contents hide
1. How Can High Blood Pressure Damage Kidneys?
1.1. Symptoms of Kidney Damage and Hypertension
2. The Expert Diagnosis
2.1. Prevention and treatment
3. Conclusion

How Can High Blood Pressure Damage Kidneys?

Kidney damage and high blood pressure can be caused by one another. However, the fact is hypertension and diabetes are the leading causes of kidney failure.

High blood pressure causes vascular constriction. In the long run, this leads to organ damage due to weakened or damaged vessels throughout your body.

Damage to kidney vessels impairs the organ’s ability to filter blood and perform other vital functions. This includes removing toxins and waste in your system.

The additional fluids in your blood can further elevate high blood pressure. If left uncontrolled, this can cause kidneys to stop working entirely.

Symptoms of Kidney Damage and Hypertension

Early stages of kidney disease may be symptom-free, like hypertension. However, swelling (edema), nausea, loss of appetite, urination difficulty, and an inability to concentrate are vital indicators of renal problems.

Patients may require dialysis or a kidney transplant if an end-stage diagnosis is made. Symptoms include:

  • Nausea or vomiting
  • Appetite and weight loss
  • Fatigue
  • Muscle cramping
  • Dry, numb, or darkened skin
  • Changes in urination frequency
  • Headaches
  • Difficulty breathing or chest pain

The Expert Diagnosis

Consistent pressure over 130/80 means hypertension according to blood pressure charts. However, like high blood pressure, kidney damage usually goes undetected.

The rate at which waste is eliminated from the body reflects kidney function.

To determine kidney health, your doctor will conduct blood tests for urea nitrogen, serum creatinine, and glomerular filtration rate. Kidney disease can also elevate protein levels like albumin in the urine.

Prevention and treatment

Lifestyle (including dietary) modifications and the addition of supplements to lower blood pressure are the first line of defense to prevent and treat both diseases.

In addition to exercise, quitting smoking, managing weight, and mental health care, certain prescription medications are aimed at people risking kidney damage. Simply put, there are many effective ways to lower and maintain hypertension that reduce this risk significantly.

Treatment options include:

ACE Inhibitors

Angiotensin-converting enzyme (ACE) inhibitors reduce enzyme production to prevent vascular constriction.

ARBs

Prevent binding of angiotensin and receptors that constrict vessels.

Beta-Blockers

Reduce heart rate, blood flow, and hormones that cause hypertension. 

Diuretics

Also known as water pills, this medication encourages the removal of excess sodium and waste fluids.

Alpha-2 Agonists

Relaxes nerve impulses to relax blood vessels.

Conclusion

A potential outcome of hypertension is damage to blood vessels and organs such as the kidneys. In addition, a delay in receiving treatment increases the risk of waste fluid build-up, which elevates the chance of complications and, ultimately, renal failure.

If your doctor has diagnosed you with hypertension, you might be recommended adaptations to your lifestyle and medications. It’s vital to take prescription drugs as indicated and attend follow-ups as scheduled to check blood pressure.

References
  • “High Blood Pressure & Kidney Disease.” National Institute of Diabetes and Digestive and Kidney Diseases (2020) https://www.niddk.nih.gov/health-information/kidney-disease/high-blood-pressure
  • Sica, D. A. “The Kidney and Hypertension: Causes and Treatment.” The Journal of Clinical Hypertension 10.7 (2008): 541-548. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110067/
  • Cha, R. et al. “The influence of blood pressure patterns on renal outcomes in patients with chronic kidney disease.” Medicine (Baltimore) 99.8 (2020). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034700/
  • Vaes, B. et al. “The correlation between blood pressure and kidney function decline in older people: a registry-based cohort study.” BMJ Open 5.6 (2015). https://bmjopen.bmj.com/content/5/6/e007571
  • “How High Blood Pressure Can Lead to Kidney Damage or Failure.” American Heart Association (2022). https://www.heart.org/en/health-topics/high-blood-pressure/health-threats-from-high-blood-pressure/how-high-blood-pressure-can-lead-to-kidney-damage-or-failure
  • Bidani, A.K. and Griffin, K.A. “Pathophysiology of Hypertensive Renal Damage.” Hypertension 44.5 (2004): 595-601. https://www.ahajournals.org/doi/full/10.1161/01.HYP.0000145180.38707.84
  • Pugh, D., Gallacher, P. J and Dhaun, N. “Management of Hypertension in Chronic Kidney Disease.” Drugs 79.4 (2019): 365-379. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422950/

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Michael Rotman, MD, FRCPC, PhD

About Michael Rotman, MD, FRCPC, PhD

Michael Rotman is a Structural Heart Specialist, Interventional Cardiologist and Scientist. He has more than a decade of experience in treating heart related desease, as well as authoring and reviewing health and wellness-related content. Currently work for a St. Michael’s Hospital in Toronto.

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Fact checked by Robin Backlund, BHSc

robin backlundRobin Backlund is a dedicated journalist and a medical student who has written several articles and essays exposing the falseness and hollowness of online resources in the medical science niche.

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Deepen Your Knowledge of Blood Pressure

We share digestible, expert-backed resources and tips to support you on your wellness journey.

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Deepen Your Knowledge of Blood Pressure

We share digestible, expert-backed resources and tips to support you on your wellness journey.

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